The removal of a genetic roadblock could improve the efficiency of converting adult cells into stem cells by 10 to 30 times, report scientists from The Methodist Hospital Research Institute and two other institutions in the latest issue of Cell.
"The discovery six years ago that scientists can convert adult cells into inducible pluripotent stem cells, or iPSCs, bolstered the dream that a patient's own cells might be reprogrammed to make patient-specific iPSCs for regenerative medicine, modeling human diseases in petri dishes, and drug screening," said Rongfu Wang, Ph.D., Principal Investigator and Director of the Center for Inflammation and Epigenetics. "But reprogramming efficiency has remained very low, impeding its applications in the clinic."
For further reading refer to http://www.sciencedaily.com/releases/2013/03/130301153247.htm
"The discovery six years ago that scientists can convert adult cells into inducible pluripotent stem cells, or iPSCs, bolstered the dream that a patient's own cells might be reprogrammed to make patient-specific iPSCs for regenerative medicine, modeling human diseases in petri dishes, and drug screening," said Rongfu Wang, Ph.D., Principal Investigator and Director of the Center for Inflammation and Epigenetics. "But reprogramming efficiency has remained very low, impeding its applications in the clinic."
For further reading refer to http://www.sciencedaily.com/releases/2013/03/130301153247.htm
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